NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Olink Explore HT Analytical Performance (Mt Sinai)   Add to my SOP compendium

BRD ID: 3,385

Source: CIMAC-CIDC Network Tier: SOP Number of times downloaded: 2

Description

This assay analytical validation and performance report describes the methods used to validate an Olink multiplex immunoassay (specifically using the Olink Explore HT Kit) to analyze levels of 5,416 proteins in EDTA plasma. The document also presents data supporting the accuracy, precision, analytical sensitivity and specificity of the assay. Further, the document presents data on the effects of heterophilic antibodies, bilirubin, lipids and hemolysate on assay performance. It is used by a Cancer Immune Monitoring and Analysis Center (CIMAC) at Mount Sinai. It is a product of the CIMAC and Cancer Immunologic Data Center Network (CIMAC-CIDC Network; https://dctd.cancer.gov/ResearchNetworks/cimacs_cidc_network.htm).

Documents for Download

508C_CIMACOlinkExploreHT_AnalyticalValidationV3_03312025 Final w coverpage.pdf [Size: 1303 KB]

Biospecimens
  • Fluid - Plasma
Diagnoses
  • General
  • Other diagnoses
  • Neoplastic
  • Normal
Topics
  • Platform-specific Methodology

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