MALDI Glycan Analytical Validation (Stanford)
BRD ID: 3,384
Source: CIMAC-CIDC Network Tier: SOP
Description
This assay analytical validation and performance report describes the methods used to validate a matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) method for the analysis of N-glycans in formalin-fixed, paraffin-embedded tissue. MALDI-IMS data from four kidney specimens were presented in conjunction with images of corresponding H&E stained FFPE sections in support of the accuracy, precision, robustness, and reproducibility of the assay. The report is used by the Cancer Immune Monitoring and Analysis Center (CIMAC) at Stanford University. It is a product of the Cancer Immune Monitoring and Analysis Center Cancer Immunologic Data Center Network (CIMAC-CIDC Network); https://dctd.cancer.gov/ResearchNetworks/cimacs_cidc_network.htm).
Documents for Download
508C_MALDI-Glycan_Validation_2024 final w coverpage.pdf [Size: 4499 KB]Biospecimens
- Tissue - Kidney
Diagnoses
- Neoplastic - Carcinoma
- Normal
- Other diagnoses
- General
Topics
- Platform-specific Methodology
Associated SOP Compendiums
- Platform-specific Methodology