NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

scRNAseq: Single-Cell RNA sequencing Analytical Performance (Mt Sinai)   Add to my SOP compendium

BRD ID: 3,115

Source: CIMAC-CIDC Network Tier: SOP Number of times downloaded: 70

Description

This assay analytical validation and performance report describes the methods used to validate a single cell RNA sequencing (scRNAseq) platform using a 10x Genomics Chromium workflow to analyze gene expression in peripheral blood mononuclear cells (PBMCs), bone marrow mononuclear cells, tumor, and tissue specimens. The document also presents data supporting the reported accuracy, precision, and analytical sensitivity. It is used by a Cancer Immune Monitoring and Analysis Center (CIMAC) at the Icahn School of Medicine at Mount Sinai. It is a product of the CIMAC and Cancer Immunologic Data Center Network (CIMAC-CIDC Network; https://dctd.cancer.gov/ResearchNetworks/cimacs_cidc_network.htm), a Cancer Moonshot Initiative.

Documents for Download

Analytical report_scRNAseq_03132023_Mt Sinai_Final.pdf [Size: 2157 KB]

Biospecimens
  • Cell - White Cells
  • Cell - Bone Marrow
  • Tissue - Not specified
Diagnoses
  • Normal
  • Neoplastic - Other
Topics
  • Platform-specific Methodology

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