Spatial transcriptomics: NanoString GeoMx Digital Spatial Profiling Analytical Validation of Immmuno-oncology Protein Targets (MDACC)
BRD ID: 3,105
Source: CIMAC-CIDC Network Tier: SOP Number of times downloaded: 8
Description
This assay analytical validation and performance report describes the methods used to validate the Nanostring GeoMx Digital Spatial Profiling (DSP) Assay using formalin-fixed, paraffin-embedded (FFPE) normal tonsil, lung adenocarcinoma, specimens represented on a tissue microarray (normal and tumor, peripheral blood mononuclear cell (PBMC) specimens). The document also presents data supporting the reported accuracy, inter- and intra-assay reproducibility, and analytical sensitivity and specificity. It is used by a Cancer Immune Monitoring and Analysis Center (CIMAC) at MD Anderson Cancer Center. It is a product of the CIMAC and Cancer Immunologic Data Center Network (CIMAC-CIDC Network; https://dctd.cancer.gov/ResearchNetworks/cimacs_cidc_network.htm), a Cancer Moonshot Initiative.
Documents for Download
Analytical Report_GeoMx_082123_MDACC_508_Final.pdf [Size: 1795 KB]Biospecimens
- Tissue - Tonsil
- Tissue - Lung
- Tissue - Spleen
- Tissue - Pancreas
- Tissue - Placenta
- Tissue - Brain
- Tissue - Ovary
- Tissue - Colorectal
- Tissue - Skin
- Tissue - Lymph Node
- Tissue - Liver
- Cell - White Cells
Diagnoses
- Normal
- Neoplastic - Carcinoma
- Neoplastic - Lymphoma
Topics
- Platform-specific Methodology
Associated SOP Compendiums
- Platform-specific Methodology