NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Tumor Biopsy Protein Extraction for Immunoassays   Add to my SOP compendium

BRD ID: 3,026

Source: DCTD Tier: SOP Number of times downloaded: 106

Description

This document describes the preparation of tissue lysates from frozen needle tumor biopsies and protein quantification by the Bradford Protein Assay for subsequent analyte quantification by enzyme-linked immunosorbent assay (ELISA) or Luminex assay for pharmacodynamic studies. It is a product of the National Cancer Institute's (NCI) Division of Cancer Treatment and Diagnosis (DCTD). Visit the DCTD website (https://dctd.cancer.gov/ResearchResources/ResearchResources-biomarkers.htm) for recent updates to the SOP.

Documents for Download

SOP341210_Immunoassay_tumor_extraction.pdf [Size: 1213 KB]

Biospecimens
  • Tissue - Not specified
Diagnoses
  • Neoplastic - Not specified
Topics
  • Biospecimen Processing
  • Analyte Extraction and Purification
  • Platform-specific Methodology

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