NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Initial Culture and Sub-culture of Patient-Derived Cancer-Associated Fibroblasts (CAFs)   Add to my SOP compendium

BRD ID: 2,279

Source: PDMR Tier: SOP Number of times downloaded: 560

Description

This document describes the procedures used by the Biological Testing Branch (BTB) for establishing primary cancer-associated fibroblast (CAF) cultures from cryopreserved patient-derived tumor tissue at NCI-Frederick, Frederick National Laboratory for Cancer Research. It also includes steps for the subculture and cryopreservation of CAFs. It is a product of the National Cancer Institute's (NCI) Patient-Derived Models Repository (PDMR) and is available at https://pdmr.cancer.gov/sops/default.htm.

Documents for Download

SOP30105_PDMR_CAF_Methodology.pdf [Size: 887 KB]

Biospecimens
  • Patient Derived Model - General
Diagnoses
  • Neoplastic - Not specified
Topics
  • Biospecimen Processing
  • Biospecimen Preservation
  • Platform-specific Methodology

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