NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Precursor Frequency Determination Using CFSE Dilution Assay and Quantification of Cytokine Secreting Cells Using Intracellular Cytokine Staining    Add to my SOP compendium

BRD ID: 1,373

Source: Immune Tolerance Network Tier: SOP Number of times downloaded: 1038

Description

This document describes procedures for preparation of frozen peripheral blood mononuclear cells (PBMC) for the carboxyfluorescein succinimidyl ester (CFSE) dilution assay and the intracellular cytokine staining (ICS) assay using flow cytometry. It is a product of the Immune Tolerance Network (ITN; https://www.immunetolerance.org/). Additional ITN SOPs are available at https://www.immunetolerance.org/researchers/lab-protocols.

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Biospecimens
  • Cell - White Cells
Diagnoses
  • General
Topics
  • Biospecimen Processing

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