Collection of SOPs from the NCI Biospecimen Pre-analytical Variables (BPV) Program
These documents describe the processes followed for the NCI Biospecimen Pre-analytical Variables (BPV) program. This research study assessed the effects of pre-analytical variables on molecular analyses of biospecimens, using a robust biospecimen collection infrastructure to prospectively collect biospecimens using SOPs to control for most variables while introducing experimental conditions to study specific biospecimen handling issues including cold ischemic time (delay to formalin fixation), time in formalin, freezing methods, and storage temperatures and durations.
The SOPs include documents relating to enrollment and informed consent; data collection, pre-operative, and evaluation forms; collection kits and the collection, processing, and packaging of biospecimens for shipment to the biorepository; histologic analysis of normal and neoplastic tissue. The SOPs are also available on the NCI BBRB website at: https://biospecimens.cancer.gov/programs/bpv/bpv_sops.asp.
Download all SOP documents of selected versions
comments powered by Disqus