Impact of the blood collection tube on the activation of coagulation.

Author(s): Polack B, Barro C, Pernod G, Bourgeat P, Vigier JP

Publication: Thromb Haemost, 1997, Vol. 77, Page 217-8

PubMed ID: 9031478 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of collection tube and anticoagulant on FVIIA levels in fresh and frozen plasma. Frozen specimens were analyzed at a different site.

   Summary of Findings:

   Fresh or frozen plasma specimens collected in Vacutainer tubes with citrate or DIATUBE-H and Venoject tubes with citrate had statistically equivalent FVIIA levels, but a wider dispersion and a trend toward a positive bias were noted in specimens collected in the Venoject tubes with citrate. Collection of plasma in Terumo Venoject DIATUBE-H tubes rather than Vacutainer citrate tubes resulted in significant effects on FVIIA levels.

   Biospecimens

   • Bodily Fluid - Plasma
   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)
   • Frozen

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Protein	Hematology/ auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Type of collection container/solution	Becton Dickinson Vacutainer Terumo Venoject
   Biospecimen Acquisition	Anticoagulant	Citrate DIATUBE-H
   Biospecimen Preservation	Type of fixation/preservation	Frozen None (fresh)

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