| Pre-analytical Factor | Classification | Bodily fluids | Cells/Tissue | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Blood | Serum | Plasma | Urine | Saliva | |||||||
| Clearing agent | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 9 | ||||
| Clearing duration/condition | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 12 | ||||
| Concentration of fixative | Biospecimen Preservation | 3 | 0 | 0 | 2 | 1 | 13 | ||||
| Conditions during fixation/preservation | Biospecimen Preservation | 2 | 0 | 0 | 0 | 0 | 0 | ||||
| Cooling or freezing method/ rate | Biospecimen Preservation | 8 | 1 | 8 | 3 | 2 | 30 | ||||
| Dehydration duration/condition | Biospecimen Preservation | 1 | 1 | 2 | 0 | 0 | 14 | ||||
| Dehydration reagent | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 6 | ||||
| Duration of tissue/ specimen processing | Biospecimen Preservation | 1 | 0 | 1 | 0 | 0 | 20 | ||||
| Embedding duration/condition | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 13 | ||||
| Embedding medium | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 26 | ||||
| Enzyme inhibitor | Biospecimen Preservation | 0 | 0 | 0 | 1 | 0 | 1 | ||||
| Fixative additive/buffer | Biospecimen Preservation | 16 | 4 | 8 | 8 | 2 | 18 | ||||
| Fixative pH | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 5 | ||||
| Kinase inhibitor | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 1 | ||||
| Method of fixative delivery | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 23 | ||||
| Method of fixative removal | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 1 | ||||
| RNA stabilization method | Biospecimen Preservation | 9 | 1 | 1 | 0 | 1 | 4 | ||||
| Temperature of fixation/preservation | Biospecimen Preservation | 2 | 0 | 1 | 0 | 0 | 27 | ||||
| Time in fixative | Biospecimen Preservation | 1 | 0 | 0 | 0 | 0 | 163 | ||||
| Tissue to fixative ratio | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 2 | ||||
| Type of fixation/preservation | Biospecimen Preservation | 241 | 93 | 158 | 93 | 12 | 539 | ||||
| Volume/ concentration of preservative | Biospecimen Preservation | 0 | 0 | 0 | 0 | 0 | 1 | ||||