NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

NCI BEBP: CELL-FREE DNA: BIOSPECIMEN COLLECTION AND PROCESSING   Add to my SOP compendium

BRD ID: 2,141

Source: BBRB Tier: Biospecimen Evidence-Based Practices (BEBP) Number of times downloaded: 2734

Description

This evidence-based, expert-vetted best practices document describes the collection and processing of blood for cell-free DNA (cfDNA) analysis as well as cfDNA extraction and storage. Biospecimens processed under these procedural guidelines are suitable for research and clinical analysis of cfDNA of either fetal or tumor origin and detection of both somatic and germline mutations. The BEBP document series is a product of the National Cancer Institute's Biorepositories and Biospecimen Research Branch (NCI BBRB) and can also be found on their website (https://biospecimens.cancer.gov/resources/bebp.asp).

Documents for Download

NCI BEBP - Cell-Free DNA Biospecimen Collection and Processing.pdf [Size: 1056 KB]

Biospecimens
  • Fluid - Plasma
  • Fluid - Blood
Diagnoses
  • General
  • Pregnant
  • Neoplastic
Topics
  • Biospecimen Acquisition
  • Biospecimen Processing
  • Biospecimen Preservation
  • Storage
  • Analyte Extraction and Purification

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