NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Efficacy of a new collection procedure for preventing bacterial contamination of whole-blood donations.

Author(s): Bruneau C, Perez P, Chassaigne M, Allouch P, Audurier A, Gulian C, Janus G, Boulard G, De Micco P, Salmi LR, Noel L

Publication: Transfusion, 2001, Vol. 41, Page 74-81

PubMed ID: 11161249 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of discarding the first 15 mL of a blood specimen on the rates of bacterial contamination.

Conclusion of Paper

In 2.2% of cases (76/3385), the first and/or second 15 mL aliquot of blood drawn was contaminated with bacteria. The second 15 mL aliquot of blood drawn cultured positive for bacteria in 0.6% of cases (21/3385), effectively reducing the bacterial contamination risk if the first 15 mL of blood collected were to be thrown out.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of discarding the first 15 mL of a blood specimen on the rates of bacterial contamination.

    Summary of Findings:

    In 2.2% of cases (76/3385), the first and/or second 15 mL aliquot of blood drawn was contaminated with bacteria. The second 15 mL aliquot of blood drawn cultured positive for bacteria in 0.6% of cases (21/3385), effectively reducing the bacterial contamination risk if the first 15 mL of blood collected were to be thrown out.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Cell count/volume Light microscopy
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Biospecimen Aliquots and Components Aliquot sequential collection 1st collection
    2nd collection

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