Cancer Diagnosis Program | Biorepositories and Biospecimen Research Branch

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Evaluation and advantages of an automatic magnetic mixing of syringes integrated to a whole blood gas analyser.

Author(s): Benoit MO, Paul JL

Publication: Scand J Clin Lab Invest, 2009, Vol. 69, Page 628-32

PubMed ID: 19391061 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of magnetic versus turnaround mixing on the determination of tHb and K+. Specimens were collected in SafePICO syringes and placed into the ABL 825 FLEX machine for magnetic mixing and analysis of tHb and K+, collected in an EDTA tube and mixed by turnaround mixing and analyzed for tHb on a LH750, or collected in heparinized tubes, centrifuged and analyzed for K+ on a LX20.

   Summary of Findings:

   No significant differences in tHb or K+ were found between specimens mixed and analyzed using the ABL 825 FLEX and those mixed by turn around mixing and analyzed on the LH 750 (tHb) and the LX20 (K+). However, a slight, clinically insignificant, positive bias was found for specimens analyzed on the ABL 825 FLEX machine. The authors attribute the bias to differences in the measurement methods used by the two autoanalyzers and not to differences in mixing. The authors conclude that the ABL 825 FLEX can be used for analysis of tHb and K+ in blood specimens.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Protein	Hematology/ auto analyzer
   Electrolyte/Metal	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Clinical chemistry/auto analyzer Specific	Technology platform	ABL 825 FLEX LX20 LH750

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