A comparison between haematological parameters in 'capillary' and venous blood samples from hospitalized children aged 3 months to 14 years.
Author(s): Daae LN, Hallerud M, Halvorsen S
Publication: Scand J Clin Lab Invest, 1991, Vol. 51, Page 651-4
PubMed ID: 1810025 PubMed Review Paper? No
Purpose of Paper
Conclusion of Paper
Studies
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Study Purpose
The purpose of this study was to determine the effects of venous versus capillary blood sampling on thrombocyte, erythrocyte, leukocyte, lymphocyte, granulocyte, and mononuclear cell counts, as well as hematocrit, hemoglobin concentration, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in pediatric patients. Venous blood was collected in K3EDTA Vacutainers and capillary blood (finger or heel prick) was collected into K2EDTA Microtainers.
Summary of Findings:
Erythrocyte counts, hematocrit, and hemoglobin concentrations were 2-3% higher in capillary specimens than in venous specimens. Thrombocyte counts were insignificantly lower in capillary specimens than in venous specimens. The authors state that MCV, MCH, and MCHC indices were similar between venous and capillary specimens. While the proportions of lymphocytes, granulocytes, and mononuclear cells did not differ significantly between the two specimen types, total leukocytes were about 20% higher in the capillary specimens than in the venous specimens.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Not specified
Platform:
Analyte Technology Platform Cell count/volume Hematology/ auto analyzer Protein Hematology/ auto analyzer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Anticoagulant Potassium EDTA
Multiple forms evaluated
Biospecimen Acquisition Anatomical location of blood draw Capillary
Vein
Biospecimen Acquisition Method of fluid acquisition Finger/heel prick sampling
Venipuncture