Influence of blood collection techniques on platelet function.

Author(s): Mani H, Kirchmayr K, Kläffling C, Schindewolf M, Luxembourg B, Linnemann B, Lindhoff-Last E

Publication: Platelets, 2004, Vol. 15, Page 315-8

PubMed ID: 15370102 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of using a butterfly cannula system as opposed to a straight needle on platelet function. Both the butterfly device and straight needle were 21-gauge. Platelet-rich plasma was used for analysis on the automated BCT and the manual aggregometer PAP-4 while anticoagulated whole blood was used for analysis on the PFA-100.

   Summary of Findings:

   Neither platelet aggregation response measured by the BCT or the PAP-4, nor CT measured by the PFA-100 were significantly different between specimens collected using a butterfly device and those collected using a straight needle, regardless of which aggregation inducer was used.

   Biospecimens

   • Bodily Fluid - Blood
   • Bodily Fluid - Plasma

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Normal

   Platform:

   Analyte	Technology Platform
   Cell count/volume	Hematology/ auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Hematology/ auto analyzer Specific	Reaction solution	Collagen/epinephrine Collagen/ADP ADP Collagen Arachidonic acid
   Hematology/ auto analyzer Specific	Technology platform	BCT (automated) PAP-4 (manual) PFA-100
   Biospecimen Acquisition	Method of fluid acquisition	Butterfly device Needle

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