Effect of heparin on umbilical arterial blood gases.

Author(s): Kirshon B, Moise KJ Jr

Publication: J Reprod Med, 1989, Vol. 34, Page 267-9

PubMed ID: 2715986 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of dilution and heparin concentration on blood gas analysis in arterial umbilical cord blood. Blood drawn into syringes containing a coating of 1,000 U/mL heparin was used as reference.

   Summary of Findings:

   When the syringe contained 0.2 ml of 1,000 U/mL heparin, the pCO2, bicarbonate, and base excess were lower than when the syringe contained a coating of 1,000 U/mL heparin. Use of a coating of 10,000 rather than 1,000 U/mL heparin resulted in decreased bicarbonate and base excess, and when 0.2 mL 10,000 U/mL heparin was used pH, pCO2, bicarbonate and base excess were decreased, and pO2 was increased compared to when a coating of 1,000 U/mL heparin was used.

   Biospecimens

   • Bodily Fluid - Cord Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Pregnant

   Platform:

   Analyte	Technology Platform
   Small molecule	Clinical chemistry/auto analyzer
   Gas	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Anticoagulant	Multiple concentrations evaluated Sodium heparin

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