Cancer Diagnosis Program | Biorepositories and Biospecimen Research Branch

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Genital region cleansing wipes: Effects on urine culture contamination.

Author(s): Selek MB, Bektöre B, Sezer O, Kula Atik T, Baylan O, Özyurt M

Publication: J Infect Dev Ctries, 2017, Vol. 11, Page 102-105

PubMed ID: 28141597 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   This study investigated the effects of urogenital cleansing with chlorhexidine-containing wipes on urine contamination in 2665 patients suspected of having a urinary tract infection (UTI). Midstream urine was collected from inpatients and outpatients suspected of having a UTI. Patients were randomly assigned to collect urine after cleansing with soap and water or chlorhexidine-containing wipes. Contamination was defined as growth of three or more colonies of skin flora. If one or two species were detected at >10⁵ cfu/mL or if <10⁵ cfu/mL occurred with UTI symptoms, bacteria were further identified to determine if they were skin flora or pathogenic.

   Summary of Findings:

   Use of chlorhexidine-containing wipes rather than soap and water decreased the contamination rate from 15.8% to 7.7% (P=0.0001). Importantly, the decrease in contamination with use of the wipes was observed both for male (11.8% versus 4.6%, P=0.0001) and female (17.7% versus 8.8%, P=0.0001) patients as well as for children (14% versus 8.7%, P=0.03) and (16.1% versus 7.5%, P=0.0001). 

   Biospecimens

   • Bodily Fluid - Urine

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Other diagnoses

   Platform:

   Analyte	Technology Platform
   Cell count/volume	Light microscopy
   Cell count/volume	Microbiological assay

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Method of fluid acquisition	Different urine collection procedures compared Voided urine (spot collection) Collection site preparation methods compared
   Preaquisition	Patient age	5-14 years >15 years
   Preaquisition	Patient gender	Female Male

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