NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Changes in blood gas samples produced by a pneumatic tube system.

Author(s): Collinson PO, John CM, Gaze DC, Ferrigan LF, Cramp DG

Publication: J Clin Pathol, 2002, Vol. 55, Page 105-7

PubMed ID: 11865003 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of using a pneumatic tube system (PTS) for the transportation of blood specimens prior to blood gas analysis.

Conclusion of Paper

No differences were observed in partial pressure oxygen (pO2), partial pressure carbon dioxide (pCO2), or pH measurements between specimens that were analyzed immediately after collection in the intensive care unit (ICU) and those that were hand carried to the laboratory for analysis, which was located on the same campus but a different building. No differences were observed in pCO2 or pH measurements between specimens analyzed immediately in the ICU and those analyzed after PTS transport in non-pressure sealed containers to the laboratory, but transport by PTS significantly increased pO2. The difference in pO2 was not correlated with the delay between sampling and analysis for transported specimens. When pressure sealed containers were used for PTS transport, no significant differences were seen in pCO2, pH, or pO2 compared to immediately analyzed specimens.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of using a PTS for the transportation of blood specimens prior to blood gas analysis. In addition, the effects of using pressure sealed and non-pressure sealed containers on blood gas analysis were investigated.

    Summary of Findings:

    No differences were observed in pO2, pCO2, or pH measurements between specimens that were analyzed immediately after collection in the ICU on a Corning 850 blood gas analyzer and those that were hand carried to the laboratory for analysis using an ABL 50 blood gas analyzer. Further, no differences were observed in pCO2 or pH measurements between specimens analyzed immediately in the ICU and those analyzed after PTS transport (average 19 min) in non-pressure or pressure sealed containers to the laboratory. However, transport by PTS in a non-pressure sealed container significantly increased pO2 with a median difference of 2.31 kPa observed (p<0.0001), but pO2 was unaffected by PTS transport in a pressure sealed container. This difference in pO2 with transport in a non-pressure sealed container was not correlated with the delay between sampling and analysis for transported specimens.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Gas Clinical chemistry/auto analyzer
    Small molecule Clinical chemistry/auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Clinical chemistry/auto analyzer Specific Technology platform ABL 50 blood gas analyzer
    Corning 850 blood gas analyzer
    Storage Within hospital transportation method Not transported
    Pneumatic tube system
    Hand-delivered
    Storage Specimen transport duration/condition Pressure sealed container
    Non-pressure sealed container

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