Comparison of two blood sampling methods in anticoagulation therapy: venipuncture and peripheral venous catheter.
Author(s): Zengin N, Enç N
Publication: J Clin Nurs, 2008, Vol. 17, Page 386-93
PubMed ID: 17394539 PubMed Review Paper? No
Purpose of Paper
Conclusion of Paper
Studies
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Study Purpose
The purpose of this study was to compare PT and APTT between specimens obtained by venipuncture and through a peripheral venous catheter from patients undergoing anticoagulation therapy.
Summary of Findings:
While there were no significant differences in APTT between venipuncture specimens and specimens obtained through 18 or 22-gauge peripheral venous catheters, specimens obtained through a 20-gauge catheter had significantly shorter APTTs than venipuncture specimens (39.36 sec versus 40.44 sec). In addition, when specimens were evaluated based on the day of sampling, specimens obtained with both 18 and 20-gauge peripheral venous catheters had significantly shorter APTTs than venipuncture specimens on the first day of the catheter, while no differences were seen for any gauge catheter on the second day. No differences were observed in PT between peripheral venous catheter specimens and venipuncture specimens, regardless of catheter gauge or day of sampling. Discarding 1 or 2 mL of blood from the peripheral venous catheter before specimen collection did not affect APTT or PT values.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Cardiovascular Disease
Platform:
Analyte Technology Platform Morphology Hematology/ auto analyzer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Method of fluid acquisition Venipuncture
IV catheter
Biospecimen Acquisition Cannulation 18-gauge catheter
20-gauge catheter
22-gauge catheter
21-gauge needle (venipuncture)
Biospecimen Aliquots and Components Aliquot size/volume 1 mL discarded
2 mL discarded
Biospecimen Acquisition Time of biospecimen collection 1st day of catheter
2nd day of catheter