Different collection tubes in cardiac biomarkers detection.
Author(s): Daves M, Trevisan D, Cemin R
Publication: J Clin Lab Anal, 2008, Vol. 22, Page 391-4
PubMed ID: 19021266 PubMed Review Paper? No
Purpose of Paper
The purpose of this paper was to determine the effects of anticoagulant and gel-separator on detection of cardiac biomarkers in blood specimens from patients with acute coronary syndrome.
Conclusion of Paper
Collection tube type and anticoagulant had no effects on cardiac troponin I. Decreased myoglobin and CK-MB were found in specimens collected in heparin tubes without a gel separator compared to specimens collected in gel separator tubes with no anticoagulant.
Studies
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Study Purpose
The purpose of this study was to determine the effects of heparin and gel separator tubes on the detection of cardiac troponin I, myoglobin ad CK-MB in blood specimens from patients with acute coronary syndrome.
Summary of Findings:
Collection tube type and anticoagulant had no effects on cardiac troponin I. Decreased myoglobin and CK-MB were found in specimens collected in heparin tubes without a gel separator compared to specimens collected in gel separator tubes with no anticoagulant.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Coronary Artery Disease
Platform:
Analyte Technology Platform Protein Immunoassay Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Type of collection container/solution Gel separator
Plain
Biospecimen Acquisition Anticoagulant Heparin
None
Immunoassay Specific Targeted peptide/protein Cardiac troponin I
Myoglobin
CK-MB