Comparison between siliconized evacuated glass and plastic blood collection tubes for prothrombin time and activated partial thromboplastin time assay in normal patients, patients on oral anticoagulant therapy and patients with unfractioned heparin therapy.

Author(s): D'Angelo G, Villa C

Publication: Int J Lab Hematol, 2011, Vol. 33, Page 219-25

PubMed ID: 20979595 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of collection tube type on PT and aPTT in platelet poor plasma from normal individuals and those on oral anticoagulant therapy.

   Summary of Findings:

   In platelet poor plasma from normal patients and those being treated with unfractionated heparin, aPTT test results were not statistically different between collection tube types. In normal patients and those being treated with oral anticoagulant therapy with vitamin K antagonists, PT was longer when platelet poor plasma was collected in Kima and Greiner plastic tubes than when collected in BD glass tubes or Terumo plastic tubes. There was also a high correlation between PT in Terumo and BD tubes (r2=0.97).

   Biospecimens

   • Bodily Fluid - Blood
   • Bodily Fluid - Plasma

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Normal
   • Not specified

   Platform:

   Analyte	Technology Platform
   Morphology	Hematology/ auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Type of collection container/solution	BD glass Greiner plastic Terumo plastic Kima plastic
   Preaquisition	Other drugs	No oral anticoagulant therapy Vitamin K antagonists Unfractionated heparin

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