Measurement of prothrombin time in patients on oral anticoagulant therapy: effect of two different evacuated tubes.

Author(s): D'Angelo G, Villa C

Publication: Haematologica, 1999, Vol. 84, Page 656-7

PubMed ID: 10406912 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to compare PT in specimens from patients on oral anticoagulant therapy collected in glass Vacutainer tubes with those collected in Venoject II tubes. The effects of using tubes at the end of their shelf life and leaving tubes out of their pouch for an extended time were also investigated.

   Summary of Findings:

   Regardless of whether tubes were used at the end of their shelf life or not, or whether the tubes were kept out of their pouch for 30 days (maximum recommended by manufacturer) or not, PT tests results were always 10-30% longer when Venoject II tubes were used for collection compared to glass Vacutainer tubes.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Morphology	Hematology/ auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Type of collection container/solution	Glass Vacutainer tubes Venoject II tubes Venoject II at the end of shelf life Venoject II kept out of pouch 30 days Venoject II kept out of pouch for 30 days and at the end of shelf life

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