NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Finger-prick--an alternative to venipuncture for the assessment of endocrine profiles in women.

Author(s): McLoughlin JW, Goodchild KS, Norman RJ

Publication: Fertil Steril, 1994, Vol. 62, Page 886-8

PubMed ID: 7926105 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of measuring estradiol (E2), progesterone (P), and luteinizing hormone (LH) in capillary rather than venous plasma specimens.

Conclusion of Paper

There were no significant differences between E2, P, and LH measurements taken using capillary rather than venous plasma.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of measuring E2, P, and LH in capillary rather than venous plasma specimens.

    Summary of Findings:

    The E2, P, and LH levels measured in plasma from capillary and venous specimens were significantly correlated (r=0.987, r=0.997, and r=0.967, respectively), and percentage differences between the two collection methods were within coefficients of variation for the E2 and P assays. For LH, the percentage differences were 2.4% higher than the maximum coefficient of variation for the assay, but the authors state they were within an acceptable precision range for the assay.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Other diagnoses
    Platform:
    AnalyteTechnology Platform
    Steroid Radioimmunoassay
    Glycoprotein Immunoradiometric assay
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Diagnosis/ patient condition Undergoing fertility treatment
    Biospecimen Acquisition Anatomical location of blood draw Capillary
    Vein

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