Comparability of venous and capillary glucose measurements in blood.

Author(s): Colagiuri S, Sandbaek A, Carstensen B, Christensen J, Glumer C, Lauritzen T, Borch-Johnsen K

Publication: Diabet Med, 2003, Vol. 20, Page 953-6

PubMed ID: 14632723 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of measuring glucose in venous plasma versus capillary whole blood from patients after fasting, 2 h post glucose consumption, or from non-selected patients. Two capillary specimens were obtained from two different sites and two venous specimens were obtained from a single venipuncture. Venous plasma was collected in tubes containing heparin and sodium fluoride.

   Summary of Findings:

   Glucose levels in capillary specimens had the smallest analytical variance when collected from fasting individuals and largest variance when collected 2 h after glucose consumption. Venous plasma collected randomly or after fasting had consistently higher glucose levels than capillary whole blood collected at equivalent times, but specimens collected 2 h post glucose consumption had lower glucose levels than capillary whole blood also collected post glucose consumption.

   Biospecimens

   • Bodily Fluid - Blood
   • Bodily Fluid - Plasma

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Carbohydrate	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Aliquots and Components	Blood and blood products	Plasma Whole blood
   Biospecimen Acquisition	Time of biospecimen collection	After fasting Random 2 h after oral glucose consumption
   Biospecimen Acquisition	Anatomical location of blood draw	Capillary Vein

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