False-positive urine cultures using bag collection.
Author(s): Grisaru-Soen G, Goldman R, Barzilai A, Lotan D, Keller N
Publication: Clin Pediatr (Phila), 2000, Vol. 39, Page 499-500
PubMed ID: 10961824 PubMed Review Paper? No
Purpose of Paper
This paper investigated diagnostic accuracy using urine collected in bags rather than by suprapubic aspiration (SPA) in 50 infants suspected of having urinary tract infection (UTI) or with fever necessitating urinalysis.
Conclusion of Paper
Using the diagnosis of the SPA specimen as the standard, the bag specimen had a sensitivity of 100%, a specificity of 30%, a positive predictive value of 19%, and a negative predictive value of 100%.
Studies
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Study Purpose
This study investigated diagnostic accuracy using urine collected in bags rather than by SPA in 50 infants (age 0-18 months) suspected of having urinary tract infection or with fever necessitating urinalysis. Urine was collected first by suprapubic aspiration (SPA) and then by bag from infants with suspected UTI who were not taking antibiotics. Thresholds for culture growth were not specified.
Summary of Findings:
Pure bacterial growth was found in 7 of 50 SPA specimens and 14 of 50 bag specimens. Mixed growth occurred in 23 bag specimens, 22 of which had no growth in the SPA. Using the SPA specimen as the standard, the bag specimen had a sensitivity and negative predictive value of 100%, but a specificity of only 30%, and a positive predictive value of 19%.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Other diagnoses
Platform:
Analyte Technology Platform Cell count/volume Light microscopy Cell count/volume Microbiological assay Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Method of fluid acquisition Different urine collection procedures compared
Needle
Voided urine (spot collection)