NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Venous stasis and routine hematologic testing.

Author(s): Lippi G, Salvagno GL, Montagnana M, Franchini M, Guidi GC

Publication: Clin Lab Haematol, 2006, Vol. 28, Page 332-7

PubMed ID: 16999725 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine if venous stasis, generated by a sphygmometer (0-3 min), influences routine hematological analytes.

Conclusion of Paper

After 1 min and 3 min of induced venous stasis, 7 and 10 of the 14 hematological parameters investigated differed significantly from no stasis controls, respectively.

Studies

  1. Study Purpose

    The purpose of this study was to determine if venous stasis, generated by a sphygmometer (0-3 min), influences routine hematological analytes.

    Summary of Findings:

    The following parameters were significantly affected by an induced venous stasis of 1 minute: white blood cell count, red blood cell count, hemoglobin, hematocrit, and lymphocyte and monocyte counts. After 3 minutes of induced venous stasis all investigated parameters differed from paired time zero controls with the following exceptions: main cell volume, main hemoglobin content, mean platelet volume, and basophil count. While red blood cell count, hemoglobin, and hematocrit increased with the duration of venous stasis, total white blood cell counts and subpopulations decreased.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Normal
    Platform:
    AnalyteTechnology Platform
    Cell count/volume Hematology/ auto analyzer
    Protein Hematology/ auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Blood pressure Venous stasis (0 min)
    Venous stasis (1 min)
    Venous stasis (3 min)

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