Comparison of blood counts in venous, fingertip and arterial blood and their measurement variation.
Author(s): Yang ZW, Yang SH, Chen L, Qu J, Zhu J, Tang Z
Publication: Clin Lab Haematol, 2001, Vol. 23, Page 155-9
PubMed ID: 11553055 PubMed Review Paper? No
Purpose of Paper
The purpose of this paper was to determine if cell counts, hemoglobin concentration, and hemocrit values are influenced by the location of blood draw (venous, arterial, capillary) or sequential collection.
Conclusion of Paper
Venous blood showed significantly higher erythrocyte counts and hemocrit than arterial blood. Capillary biospecimens contained higher total and large leucocyte counts. Measurements in venous blood showed lower coefficients of variation than capillary or arterial blood measurements. Significant differences among sequentially collected aliquots were limited to total leucocyte counts of fingertip collected specimens.
Studies
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Study Purpose
The purpose of this study was to determine if cell counts, hemoglobin concentration, and hemocrit values are influenced by the location of blood draw (venous, arterial, capillary).
Summary of Findings:
Total leucocyte count and large leucocyte ratio were significantly higher in capillary compared to venous blood specimens. Erythrocyte count and hemocrit values were significantly lower in arterial compared to venous blood specimens. Statistical significance was unaffected whether pooled means or individual samples were compared. Capillary and arterial blood specimens exhibited greater variance for analyzed parameters than venous blood specimens.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Not specified
Platform:
Analyte Technology Platform Cell count/volume Hematology/ auto analyzer Protein Hematology/ auto analyzer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Anatomical location of blood draw Artery
Capillary
Vein
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Study Purpose
The purpose of this study was to evaluate whether significant differences would be observed among hematological factors in sequentially collected fingertip blood specimens.
Summary of Findings:
White-blood-cell related parameters differed significantly among first, second, and third fingertip blood specimens.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Not specified
Platform:
Analyte Technology Platform Cell count/volume Hematology/ auto analyzer Protein Hematology/ auto analyzer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Aliquots and Components Aliquot sequential collection 1st collection
2nd collection
3rd collection