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Serum soluble transferrin receptor concentrations in US preschool children and non-pregnant women of childbearing age from the National Health and Nutrition Examination Survey 2003-2010.

Author(s): Mei Z, Pfeiffer CM, Looker AC, Flores-Ayala RC, Lacher DA, Mirel LB, Grummer-Strawn LM

Publication: Clin Chim Acta, 2012, Vol. 413, Page 1479-84

PubMed ID: 22705806 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of patient age, gender, parity, education level, income, and ethnicity on soluble transferrin receptor (sTfR) levels in serum.

Conclusion of Paper

Serum from children had significantly higher levels of sTfR than serum from women of childbearing age. Further, among the children, higher serum levels of sTfR were found in 1-2 year olds than 3-5 year olds, boys than girls, and non-hispanic blacks than other ethnicities. Specimens from 20-49 year old women had lower levels of sTfR than specimens from 15-19 year old women after adjusting for socio-demographic variables. Serum from non-hispanic black women had the highest levels of sTfR while serum from non-hispanic white women had the lowest levels of sTfR. Serum from women who had given birth 2 or more times contained higher levels of sTfR than serum from women who had never given birth. After adjustment for socio-demographic variables, neither patient education level, nor family income had effects on sTfR levels.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of patient age, gender, parity, education level, income, and ethnicity on sTfR levels in serum. Both male and female children were included in the study, however, only non-pregnant women of childbearing age (15-49) were included.

    Summary of Findings:

    Serum from children (1-5 y) had significantly higher levels of sTfR than serum from women of childbearing age (15-49 y). Levels of sTfR were higher in the serum from 1-2 year olds than 3-5 year olds, boys than girls, and non-hispanic blacks than other ethnicities. Specimens from 20-49 year old women had lower levels of sTfR than specimens from 15-19 year old women after adjusting for socio-demographic variables. Serum from non-hispanic black women had the highest levels of sTfR while serum from non-hispanic white women had the lowest levels of sTfR. Serum from women who had given birth 2 or more times contained higher levels of sTfR than serum from women who had never given birth. After adjustment for socio-demographic variables, neither patient education level, nor family income had effects on sTfR levels.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Normal
    Platform:
    AnalyteTechnology Platform
    Protein Clinical chemistry/auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Patient age 1-2 y
    3-5 y
    15-19 y
    20-34 y
    35-49 y
    Preaquisition Patient gender Female
    Male
    Preaquisition Prior patient medical condition 0 pregnancies resulting in a birth
    1 birth
    2 or more births
    Preaquisition Patient race Non-hispanic white
    Non-hispanic black
    Mexican-American
    View more

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