Cancer Diagnosis Program | Biorepositories and Biospecimen Research Branch

Search BRD Papers

Influence of centrifuge temperature on routine coagulation testing.

Author(s): Lippi G, Salvagno GL, Montagnana M, Poli G, Guidi GC

Publication: Clin Chem, 2006, Vol. 52, Page 537-8

PubMed ID: 16510437 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of centrifugation temperature on coagulation testing. Blood was collected from 14 healthy volunteers and 13 patients on oral anticoagulant therapy in trisodium citrate tubes. Specimens were centrifuged first at 4 degrees C followed by 12 degrees C and then room temperature. All centrifugation was for 10 min at 1500 x g at each temperature.

   Summary of Findings:

   Centrifugation temperature did not impact aPTT, PT, fibrinogen or D-dimer measurements.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Normal
   • Not specified

   Platform:

   Analyte	Technology Platform
   Glycoprotein	Hematology/ auto analyzer
   Morphology	Hematology/ auto analyzer
   Peptide	ELISA

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Aliquots and Components	Centrifugation	Multiple temperatures compared

   View more