Plastic vs glass SST evacuated serum-separator blood-drawing tubes for endocrinologic analytes.
Author(s): Reinartz JJ, Ramey ML, Fowler MC, Killeen AA
Publication: Clin Chem, 1993, Vol. 39, Page 2535-6
PubMed ID: 8252733 PubMed Review Paper? No
Purpose of Paper
Conclusion of Paper
The purpose of this study was to compare 11 endocrinologic endpoints in blood collected in plastic versus glass SST and in plain versus SST glass tubes. Aldosterone, cortisol, DHEAS, estradiol, progesterone, 17-OH progesterone, free and total testosterone, thyroid hormone binding ratio, thyroxine and triiodothyronine were quantified for this study. Serum specimens were stored at -25 degrees C for less than 2 weeks prior to analysis.
Summary of Findings:
No significant differences were observed between plastic and glass SST tubes. Blood specimens collected in plain glass had lower DHEAS (p=0.01) and higher estradiol (p=0.04), but the authors were unsure if the changes were clinically significant.
Analyte Technology Platform Steroid Radioimmunoassay Peptide Radioimmunoassay Peptide Immunoassay Steroid Immunoassay Steroid Equilibrium dialysis
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Type of collection container/solution Plain glass tube
Vacutainer SST tube (serum separator glass)
Vacutainer plus SST tube (plastic serum separator)