NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Ethylbenzene and xylene from Sarstedt Monovette serum gel blood-collection tubes.

Author(s): Streete PJ, Flanagan RJ

Publication: Clin Chem, 1993, Vol. 39, Page 1344-5

PubMed ID: 8504548 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the source of ethylbenzene and xylene contamination of whole blood.

Conclusion of Paper

Storage of blood at room temperature for 96 h in Monovette tubes resulted in measureable levels of o-xylene, ethylbenzene, and m-xylene. The magnitude of the increase was dependent on the age of the tubes with tubes furthest from expiration having the largest effect.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of storing blood in Starstedt Monovette tubes on the quantification of ethylbenzene and xylene. Expired volatile-free hemolyzed blood-bank whole blood was used for all assays.

    Summary of Findings:

    Storage of blood at room temperature for 96 h in Monovette tubes resulted in measureable levels of o-xylene, ethylbenzene, and m-xylene. The magnitude of the increase was dependent on the age of the tubes with tubes furthest from expiration having the largest effect. The authors report that Starstedt Monovette serum gel tubes, and Becton Dickinson Vacutainer STT gel and clot activator tubes do not cause an increase in the concentration of volatiles.

    Biospecimens
    Preservative Types
    • Frozen
    Diagnoses:
    • Normal
    Platform:
    AnalyteTechnology Platform
    Small molecule Headspace gas chromatography
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Type of storage container Starstedt Monovette serum gel tube
    Storage Time at room temperature 24 h
    96 h
    120 h

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