NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Evaluation of the polyester gel barrier Microtainer.

Author(s): Kupke IR

Publication: Clin Chem, 1987, Vol. 33, Page 1468-9

PubMed ID: 3608172 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effect of the polyester gel in microtainer tubes on 47 clinical chemistry analytes in blood.

Conclusion of Paper

Lactate dehydrogenase (LDH) was higher in specimens centrifuged in reaction tubes than in specimens centrifuged in microtainers containing polyester gel, but no clinically relevant effects on other clinical chemistry analytes were identified.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effect of the polyester gel in microtainer tubes on 47 clinical chemistry analytes in blood. Blood collected from patients and normal volunteers was distributed between tubes and centrifuged before analysis.

    Summary of Findings:

    LDH was 9% higher in specimens centrifuged in reaction tubes than in specimens centrifuged in microtainers containing polyester gel, but the authors report direct incubation of the serum with the polyester gel had no effect on LDH. Creatinine, phophatidylcholine, and alkaline phosphatase levels were significantly higher in specimens centrifuged in microtainers containing polyester gel than in reaction tubes, but the increase was not clinically relevant and the increase in phosphatidylcholine was only found in serum. The authors conclude that the polyester gel containing microtainers are suitable for all assays except measurement of LDH.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    • Normal
    Platform:
    AnalyteTechnology Platform
    Carbohydrate Clinical chemistry/auto analyzer
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Lipid Clinical chemistry/auto analyzer
    Protein Clinical chemistry/auto analyzer
    Protein Electrophoresis
    Small molecule Clinical chemistry/auto analyzer
    Steroid Clinical chemistry/auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Biospecimen Aliquots and Components Blood and blood products Serum
    Whole blood
    Storage Type of storage container Microliter reaction tubes
    Microtainer tube containing polyester gel

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