NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Evaluation of a new blood-collecting device ("microtainer") that is suited for pediatric use.

Author(s): Hicks JM, Rowland GL, Buffone GJ

Publication: Clin Chem, 1976, Vol. 22, Page 2034-6

PubMed ID: 1000802 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to evaluate microtainer tubes for clinical chemistry and hematological analysis of serum.

Conclusion of Paper

Serum collected in Microtainer tubes was free of leukocyte and platelet contamination and had no visible hemolysis. Sodium levels were lower in specimens collected in Microtainer tubes, but the difference was not clinically significant. There was no effect of storage in the Microtainer tube for up to 24 h on potassium and lactate dehydrogenase levels

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of collection tube type, and storage on clinical chemistry and hematological parameters in serum from pediatric patients.

    Summary of Findings:

    Serum collected in Microtainer tubes was free of leukocyte and platelet contamination and had no visible hemolysis. No effect of collection tube type was found on cholesterol, triglycerides, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, creatine kinase, total protein, creatinine, sodium, potassium, chloride, calcium, thyroxine, billirubin, blood urea nitrogen or phosphorus levels. Sodium levels were lower in specimens collected in Microtainer tubes, but the difference was not clinically significant. There was no effect of storage in the Microtainer tube for up to 24 h on potassium and lactate dehydrogenase levels.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Cell count/volume Light microscopy
    Protein Clinical chemistry/auto analyzer
    Lipid Clinical chemistry/auto analyzer
    Steroid Clinical chemistry/auto analyzer
    Small molecule Clinical chemistry/auto analyzer
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Gas Clinical chemistry/auto analyzer
    Electrolyte/Metal Flame emission photometry
    Peptide Radioimmunoassay
    Protein Hematology/ auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Biospecimen Acquisition Type of collection container/solution Microtainer tube
    3 mL BD tube
    Storage Storage duration 0 h
    5 h
    12 h

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