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Two site evaluation of the performance of a new generation point-of-care glucose meter for use in a neonatal intensive care unit.

Author(s): Tendl KA, Christoph J, Bohn A, Herkner KR, Pollak A, Prusa AR

Publication: Clin Chem Lab Med, 2013, Vol. 51, Page 1747-54

PubMed ID: 23612555 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of medications and levels of other clinical chemistry analytes on the levels of glucose in blood from neonatal intensive care unit (NICU) patients using two different clinical chemistry analyzers.

Conclusion of Paper

Glucose levels measured by the StatStrip glucose meter or the ABL glucose meter were very strongly correlated throughout the range of levels, but there was a small negative bias for levels measured by the StatStrip device that increased with increasing glucose levels. Hematocrit, pH, partial pressure oxygen, sodium, or medication did not affect the accuracy of glucose measurements with StatStrip (ABL used as reference).

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of medications and levels of other clinical chemistry analytes on the levels of glucose in blood from NICU patients using two different clinical chemistry analyzers. Blood was obtained by an unspecified method from 1-62 day old (23.14-41.29 weeks gestation) NICU patients. Blood was first assayed using an ABL analyzer and then with the StatStrip glucose meter.

    Summary of Findings:

    Glucose levels measured by the StatStrip glucose meter or the ABL glucose meter were very strongly correlated (r2=0.975) throughout the range of levels with a mean bias of -4.52% for levels measured by the StatStrip device. The mean StatStrip bias was -4.03% when glucose levels were <75 mg/dL and -3.07% for specimens with <45 mg/dL glucose. Hematocrit, pH, partial pressure oxygen, sodium, or medication did not affect the accuracy of glucose measurements with StatStrip (ABL used as reference).

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Cardiovascular Disease
    • Other diagnoses
    Platform:
    AnalyteTechnology Platform
    Carbohydrate Clinical chemistry/auto analyzer
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Gas Clinical chemistry/auto analyzer
    Small molecule Clinical chemistry/auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Diagnosis/ patient condition Respiratory disease
    Child of diabetic mother
    Hyperbilirubinaemia
    Congenital infection
    Necrotizing enterocolitis
    Meconium aspiration
    Prenatal asphyxia
    Congenital heart disease
    Preaquisition Other drugs Vitamin C
    Caffeine
    Paracetamol
    Preaquisition Biomarker level 13-389 mg/dL glucose
    25-77% hematocrit
    pH of 7.15-7.39
    25-59 mm Hg PO2
    122-145 mmol/L sodium
    Clinical chemistry/auto analyzer Specific Technology platform StatStrip glucose meter
    ABL glucose meter
    View more

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