NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Speed of sample transportation by a pneumatic tube system can influence the degree of hemolysis.

Author(s): Tiwari AK, Pandey P, Dixit S, Raina V

Publication: Clin Chem Lab Med, 2011, Vol. 50, Page 471-4

PubMed ID: 22070350 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of pneumatic tube system (PTS) transport and transport speed on indicators of hemolysis in blood specimens.

Conclusion of Paper

PTS transport at high speed (3 m/s) for 115 m resulted in increased lactate dehydrogenase (LD), and high speed transport for 225 m resulted in increased hemoglobin, potassium (K) and LD compared to hand-delivery, indicating high speed PTS transport induced hemolysis. PTS transport at low speed (2 m/s) for 115 m did not affect LD, K or hemoglobin compared to specimens that were hand-delivered.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of PTS transport and transport speed on levels of the hemolysis indicators LD, K and hemoglobin in blood specimens. Specimens were collected and transported in red-cap serum tubes.

    Summary of Findings:

    PTS transport at high speed (3 m/s) for 115 m resulted in increased LD, and high speed PTS transport for 225 m resulted in increased hemoglobin, K and LD compared to hand-delivery, indicating high speed PTS transport induced hemolysis. PTS transport at low speed (2 m/s) for 115 m did not affect LD, K or hemoglobin compared to specimens that were hand-delivered.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Normal
    Platform:
    AnalyteTechnology Platform
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Protein Clinical chemistry/auto analyzer
    Small molecule Clinical chemistry/auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Within hospital transportation method Hand-delivered
    Pneumatic tube system
    Storage Specimen transport duration/condition 115 m at 3 m/s
    225 m at 3 m/s
    115 m at 2 m/s

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