Cancer Diagnosis Program | Biorepositories and Biospecimen Research Branch

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Evaluation of the BD Vacutainer PST II blood collection tube for special chemistry analytes.

Author(s): Chance J, Berube J, Vandersmissen M, Blanckaert N

Publication: Clin Chem Lab Med, 2009, Vol. 47, Page 358-61

PubMed ID: 19676149 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to evaluate the effects of collection tube type and storage at room temperature on chemistry analytes. Analytes studied included thyroid stimulating hormone, free thyroxine, total thyroxine, follicle stimulating hormone, luteinizing hormone, ferritin, cortisol, vitamin B12, folate and testosterone.

   Summary of Findings:

   No clinically significant effects of glass versus plastic or gel versus non-gel collection tube on any of the tested analytes were found. Further, the use of serum versus plasma or fresh versus stored specimens did not significantly alter any of the analytes.

   Biospecimens

   • Bodily Fluid - Serum
   • Bodily Fluid - Plasma
   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Steroid	Radioimmunoassay
   Steroid	Clinical chemistry/auto analyzer
   Peptide	Clinical chemistry/auto analyzer
   Small molecule	Radioimmunoassay
   Glycoprotein	Clinical chemistry/auto analyzer
   Protein	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Type of collection container/solution	BD Vacutainer serum plus tube BD Vacutainer lithium heparin plus tube BD Vacutainer lithium heparin glass tube BD Vacutainer PST II tube
   Biospecimen Acquisition	Anticoagulant	Lithium heparin
   Biospecimen Aliquots and Components	Blood and blood products	Plasma Serum
   Storage	Time at room temperature	Less than 1 h 24 h

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