NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Preanalytical variability in laboratory testing: influence of the blood drawing technique.

Author(s): Lippi G, Salvagno GL, Brocco G, Guidi GC

Publication: Clin Chem Lab Med, 2005, Vol. 43, Page 319-25

PubMed ID: 15843239 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine if routine hematological and clinical chemistry parameters differ as a result of the type of needle used during blood draw (traditional straight needle versus butterfly device).

Conclusion of Paper

Of the 43 parameters measured, only serum sodium levels, white blood cell counts, and platelet counts significantly varied between the two blood draw techniques.

Studies

  1. Study Purpose

    The purpose of this study was to determine if routine hematological and clinical chemistry parameters differ as a result of the type of needle used during blood draw (traditional straight needle versus butterfly device).

    Summary of Findings:

    Of the 43 parameters investigated, only platelet count and white blood cell count differed significantly due to the type of blood collection device used, which were lower in specimens collected with the butterfly device compared to those collected with a straight needle. However, as determined by coefficient of variation, serum sodium also differed among differentially collected specimens.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Protein Spectrophotometry
    Protein Clinical chemistry/auto analyzer
    Steroid Clinical chemistry/auto analyzer
    Small molecule Clinical chemistry/auto analyzer
    Carbohydrate Clinical chemistry/auto analyzer
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Lipid Clinical chemistry/auto analyzer
    Cell count/volume Hematology/ auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Biospecimen Acquisition Needle gauge 21-Gauge straight needle
    21-Gauge butterfly device

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