NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

A computer directed pneumatic tube system: its effects on specimens.

Author(s): Pragay DA, Fan P, Brinkley S, Chilcote ME

Publication: Clin Biochem, 1980, Vol. 13, Page 259-61

PubMed ID: 7214692 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of pneumatic tube system (PTS) transport on clinical chemistry analytes in blood and urine specimens.

Conclusion of Paper

Lactate dehydrogenase (LD) was elevated in blood specimens from healthy individuals and patients with pulmonary diseases, cardiac problems and gastrointestinal diseases after being transported by dedicated or general PTS compared to hand-delivered specimens, but elevations were not significant for patients with neoplastic diseases. The authors report that sending clotted versus unclotted blood through the PTS did not significantly affect any analyte, and PTS transport did not affect urinary casts.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of PTS transport on 3 clinical chemistry and 3 gas analytes in blood specimens. Specimens were placed in a ziplock bag and towel wrapped before transport via a dedicated PTS or placed in a plastic bag inside a carrier with a foam insert before transport via a general PTS.

    Summary of Findings:

    LD was elevated in blood specimens from healthy individuals after being transported by dedicated or general PTS compared to specimens that were hand-delivered (p<0.001 and p<0.01, respectively). The authors report the increase in LD after PTS transport was due to small increases in LD fractions 1, 2 and 3. LD was also elevated after PTS transport in patients with pulmonary diseases (p<0.001), cardiac problems (p<0.001) and gastrointestinal diseases (p<0.05), but not in patients with neoplastic diseases. The authors report that sending clotted versus unclotted blood through the PTS did not significantly affect any analyte. PTS transport did not affect blood potassium, partial pressure carbon dioxide (PCO2), partial pressure oxygen (PO2), pH, or acid phosphatase.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Cardiovascular Disease
    • Neoplastic
    • Normal
    • Other diagnoses
    Platform:
    AnalyteTechnology Platform
    Electrolyte/Metal Flame emission photometry
    Protein Clinical chemistry/auto analyzer
    Gas Clinical chemistry/auto analyzer
    Small molecule pH
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Within hospital transportation method Hand-delivered
    Pneumatic tube system
    Storage Specimen transport duration/condition Clotted
    Not clotted
    In ziplock bag and wrapped in a towel
    In a ziplock bag in a carrier with a foam insert
    Preaquisition Diagnosis/ patient condition Pulmonary diseases
    Cardiac problems
    Gastrointestinal diseases
    Neoplastic diseases
    Normal
  2. Study Purpose

    The purpose of this study was to determine the effects of PTS transport on urinary casts.

    Summary of Findings:

    The authors report that PTS transport did not affect urinary casts compared to urine specimens that were hand-delivered.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Morphology Light microscopy
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Within hospital transportation method Hand-delivered
    Pneumatic tube system

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