NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Effects of helicopter transport on red blood cell components.

Author(s): Otani T, Oki K, Akino M, Tamura S, Naito Y, Homma C, Ikeda H, Sumita S

Publication: Blood Transfus, 2012, Vol. 10, Page 78-86

PubMed ID: 22153688 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of helicopter transport and refrigerated storage duration on leukocyte-reduced red blood cell quality parameters.

Conclusion of Paper

Regardless of transport, hematocrit (Hct) and supernatant potassium levels increased slightly, and pH, glucose and adenosine triphosphate (ATP) levels decreased slightly as refrigerated storage duration of red blood cells increased from 7 to 42 days. 2,3 diphosphoglycerate (DPG) declined rapidly between 7 and 21 days, both in the helicopter-transported specimens and those which were not transported. Supernatant hemoglobin levels and hemolysis of red blood cells increased as refrigerated storage duration increased, but after 42 days, the increase was significantly higher in the helicopter-transported specimens than in the specimens which were not transported.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of helicopter transport and refrigerated storage duration on leukocyte-reduced red blood cell quality parameters. After 7 days of refrigerated storage, half of the specimens were transported round-trip by helicopter for 4 h, with a maintained temperature of 2-6 degrees C, and then the specimens were returned to the refrigerator.

    Summary of Findings:

    Regardless of transport, Hct and supernatant potassium levels increased slightly, and pH, glucose and ATP levels decreased slightly when the duration of refrigerated storage increased from 7 to 42 days. 2,3 DPG declined rapidly between 7 and 21 days, both in the helicopter-transported specimens and those which were not transported. Supernatant hemoglobin levels and hemolysis in red blood cells increased as refrigerated storage increased, but after 42 days, the increase was significantly higher in the helicopter-transported specimens than in the specimens which were not transported.

    Biospecimens
    Preservative Types
    • Other Preservative
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Small molecule Chemiluminescence
    Small molecule Clinical chemistry/auto analyzer
    Electrolyte/Metal Clinical chemistry/auto analyzer
    Protein Hematology/ auto analyzer
    Protein Spectrophotometry
    Carbohydrate Clinical chemistry/auto analyzer
    Morphology Spectrophotometry
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Between site transportation method Helicopter
    Not transported
    Storage Storage duration 7 days
    14 days
    21 days
    42 days

You Recently Viewed  

News and Announcements

  • Most Downloaded SOPs in 2024

  • New Articles on the GTEx Project are Now FREELY Available!

  • Just Published!

  • More...