NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Arteriovenous differences of hematological and coagulation parameters in patients with sepsis.

Author(s): Durila M, Kalincik T, Jurcenko S, Pelichovská M, Hadacova I, Cvachovec K

Publication: Blood Coagul Fibrinolysis, 2010, Vol. 21, Page 770-4

PubMed ID: 20885299 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to compare hematological, thromboelastography, and coagulation parameters in arterial and venous blood specimens from patients with severe sepsis.

Conclusion of Paper

While most parameters measured were not significantly different between arterial and venous blood specimens, antithrombin activity was significantly lower and D-dimer concentrations were significantly higher in venous blood specimens compared to arterial specimens (p<0.05).

Studies

  1. Study Purpose

    The purpose of this study was to compare hematological, thromboelastography, and coagulation parameters in arterial and venous blood specimens from patients with severe sepsis.

    Summary of Findings:

    While most parameters measured were not significantly different between arterial and venous blood specimens, antithrombin activity was significantly lower and D-dimer concentrations were significantly higher in venous blood specimens compared to arterial specimens (p<0.05).

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Other diagnoses
    Platform:
    AnalyteTechnology Platform
    Cell count/volume Hematology/ auto analyzer
    Protein Hematology/ auto analyzer
    Peptide Hematology/ auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Diagnosis/ patient condition Severe sepsis
    Biospecimen Acquisition Anatomical location of blood draw Artery
    Vein

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