Pneumatic transport exacerbates interference of room air contamination in blood gas samples.

Author(s): Astles JR, Lubarsky D, Loun B, Sedor FA, Toffaletti JG

Publication: Arch Pathol Lab Med, 1996, Vol. 120, Page 642-7

PubMed ID: 8757468 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of PTS transport conditions on the PO2 of tonometered blood and blood from normal and hypoxemic patients.

   Summary of Findings:

   Air bubbles did not affect the PO2 when specimens were left undisturbed for 5 min or when specimens tonometered with 142 mm Hg O2 were transported by PTS, but they significantly increased the PO2 when specimens with less than 100 mm Hg O2 were transported by PTS and decreased the PO2 when specimens with 339 mm Hg O2 were transported by PTS. Importantly, air bubbles had a significant effect on the PO2 of specimens from both normal and hypoxemic patients. The addition of a liner during PTS did not provide protection against the changes in PO2. Removal of air from the liner bag prior to transport significantly reduced the PO2. Filling the liner bag with an ice slurry stabilized the PO2 of specimens with 342 mm Hg O2 during PTS transport but did not prevent changes in specimens with a PO2 of 81 mm Hg O2. Reducing the speed of PTS to 50% significantly reduced the effects of PTS transport on the PO2.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified
   • Other diagnoses

   Platform:

   Analyte	Technology Platform
   Gas	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Preaquisition	Diagnosis/ patient condition	Unspecified pneumatic disease Unspecified elective surgical patient Post-cardiac surgery intensive care patients
   Biospecimen Aliquots and Components	Biospecimen components	65 mm Hg O2 75 mm Hg O2 142 mm Hg O2 339 mm Hg O2 0.2 mL air bubble 0.5 mL air bubble
   Storage	Specimen transport duration/condition	Pneumatic transport with liner bag Pneumatic transport without liner bag Pneumatic transfer in water filled bag Pneumatic transfer in ice slurry filled bag Pneumatic transport at 75% of normal speed Pneumatic transport at 50% of normal speed
   Storage	Within hospital transportation method	Not transported Pneumatic tube system

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