NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Correlation of simultaneously obtained capillary, venous, and arterial blood gases of patients in a paediatric intensive care unit.

Author(s): Yildizdas, Yapicioglu, Yilmaz HL, Sertdemir Y

Publication: Arch Dis Child, 2004, Vol. 89, Page 176-80

PubMed ID: 14736638 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of patient condition and sampling location on measurement of blood gases.

Conclusion of Paper

pH, partial pressure carbon dioxide (pCO2), base excess and bicarbonate were highly correlated in arterial, venous and capillary blood and were unaffected by patient blood pressure or temperature. In normotensive and hypertensive patients, partial pressure oxygen (pO2) measurements were moderately correlated between arterial, capillary and venous blood, but in patients with hypotension, there was no correlation between arterial and venous or capillary pO2 measurements, and the correlation between pO2 in venous and capillary blood was lower.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of patient condition and sampling location on measurement of blood gases in hospitalized pediatric patients. When available, venous and arterial blood were collected by catheter. Otherwise blood was collected by puncture.

    Summary of Findings:

    pH, pCO2, base excess and bicarbonate were highly correlated in arterial, venous and capillary blood (all r>0.823; p<0.001) and were unaffected by patient blood pressure or temperature. In normotensive and hypertensive patients, pO2 measurements were moderately correlated between arterial and venous blood (r=0.366; p=0.005), capillary and venous blood (r=0.541; p<0.001), and arterial and capillary blood (r=0.674; p<0.001). However, in patients with hypotension, there was no correlation between arterial and venous or capillary pO2 measurements, and the correlation between pO2 in venous and capillary blood was lower (r=0.49, p<0.001).

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    • Other diagnoses
    Platform:
    AnalyteTechnology Platform
    Gas Clinical chemistry/auto analyzer
    Small molecule pH
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Preaquisition Blood pressure Hypotensive
    Normotensive
    Hypertensive
    Preaquisition Diagnosis/ patient condition Hypothermia
    Normothermia
    Hyperthermia
    Biospecimen Acquisition Anatomical location of blood draw Artery
    Capillary
    Vein

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