Pseudometabolic acidosis caused by underfill of Vacutainer tubes.
Author(s): Herr RD, Swanson T
Publication: Ann Emerg Med, 1992, Vol. 21, Page 177-80
PubMed ID: 1739211 PubMed Review Paper? No
Purpose of Paper
Conclusion of Paper
Studies
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Study Purpose
The purpose of this study was to determine the effects of specimen volume and venting Vacutainer tubes after specimen collection on serum bicarbonate and anion gap values in specimens from emergency department patients. The authors state that time to analysis was not controlled but reflected actual patient care.
Summary of Findings:
In both vented and unvented tubes, mean serum bicarbonate values decreased and mean anion gap increased significantly as specimen volume decreased from 10 mL to 1 mL. No significant differences in serum bicarbonate or anion gap were found between vented and unvented tubes.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Not specified
Platform:
Analyte Technology Platform Electrolyte/Metal Clinical chemistry/auto analyzer Small molecule Clinical chemistry/auto analyzer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Aliquots and Components Aliquot size/volume 10 mL
3 mL
1 mL
Storage Storage conditions Vacutainer vented after collection
Unvented Vacutainer