Measurement of plasma viscosity by free oscillation rheometry: imprecision, sample stability and establishment of a new reference range.
Author(s): Pedersen L, Nielsen EB, Christensen MK, Buchwald M, Nybo M
Publication: Ann Clin Biochem, 2013, Vol. 51, Page 495-498
PubMed ID: 24081187 PubMed Review Paper? No
Purpose of Paper
The purpose of this paper was to determine the effects of storage and patient gender on plasma viscosity.
Conclusion of Paper
Storage of plasma at 20 degrees C for 48 h, 4 degrees C for 20 days, or -20 degrees C for 3 months did not affect viscosity. There was no effect of patient gender on plasma viscosity.
Studies
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Study Purpose
The purpose of this study was to determine the effects of storage and patient gender on plasma viscosity. EDTA plasma from 20 healthy patients was stored at -20 degrees C for 3 months. After thawing specimens at 37 degrees C, plasma was then stored at 4 degrees C for 20 days, 20 degrees C for 2 days, or analyzed immediately. Reference ranges for plasma viscosity were based on plasma obtained from 585 Danish blood donors.
Summary of Findings:
Storage at 20 degrees C for 48 h, 4 degrees C for 20 days, or -20 degrees C for 3 months did not affect plasma viscosity. There was no effect of patient gender on plasma viscosity.
Biospecimens
Preservative Types
- Frozen
Diagnoses:
- Normal
Platform:
Analyte Technology Platform Morphology Rheometer Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Storage Storage temperature -20 degrees C
4 degrees C
20 degrees C
Preaquisition Patient gender Female
Male
Storage Storage duration 2 days
20 days
3 months