EFFECT OF PNEUMATIC TUBE TRANSPORT SYSTEM ON THE VALIDITY OF DETERMINATIONS IN BLOOD CHEMISTRY.

Author(s): MCCLELLAN EK, NAKAMURA RM, HAAS W, MOYER DL, KUNITAKE GM

Publication: Am J Clin Pathol, 1964, Vol. 42, Page 152-5

PubMed ID: 14202148 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to determine the effects of PTS transport on clinical chemistry analytes in blood and serum. Blood was collected into vacutainers which were sealed with rubber stoppers. During PTS transport, the tubes travelled at 25-30 ft/sec through several turns in carriers. The tubes were inserted into the carriers such that no tubes broke (stoppered end down). The significance of some of the reported changes was not evaluated.

   Summary of Findings:

   The serum hemoglobin levels in the specimens transported via PTS were 145-4150% (mean 1528%) higher than when hand-delivered (p<0.0005). While none of the PTS-transported specimens had serum hemoglobin levels in the normal range, 14 of 18 hand-delivered specimens had levels in the normal range. Serum LDH levels were 21-163% (mean 70%) higher in specimens transported by PTS than those hand-delivered. Further, 16 of 18 specimens had higher serum potassium levels after PTS transport than after hand-delivery (2-32%). Serum levels of urea nitrogen, chloride, bicarbonate, sodium, glutamic oxalacetic transaminase, and glutamic pyruvic transaminase and blood levels of alkaline phosphatase, total protein, and albumin to globulin ratio were unaffected by PTS transport.

   Biospecimens

   • Bodily Fluid - Blood
   • Bodily Fluid - Serum

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Protein	Colorimetric assay
   Protein	Clinical chemistry/auto analyzer
   Protein	Spectrophotometry
   Electrolyte/Metal	Flame emission photometry
   Electrolyte/Metal	Clinical chemistry/auto analyzer
   Small molecule	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Storage	Within hospital transportation method	Hand-delivered Pneumatic tube system
   Biospecimen Aliquots and Components	Blood and blood products	Serum Whole blood

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