Diagnostic Yield and Complications Using a 20 Gauge Prostate Biopsy Needle versus a Standard 18 Gauge Needle: A Randomized Controlled Study.
Author(s): Wang J, Wan B, Li C, Wang J, Fu Q, Zhao W, Zhang K
Publication: Urol J, 2015, Vol. 12, Page 2329-33
PubMed ID: 26571315 PubMed Review Paper? No
Purpose of Paper
This paper compared the effects of needle gauge on detection rates in prostate biopsies.
Conclusion of Paper
Detection rates for prostate cancer were comparable between specimens obtained using a standard 18-gauge needle and a 20-gauge biopsy needle; however, patients biopsied with a 20-gauge needle experienced fewer complications including pain, infection, hematuria, hematochezia, and dysuria.
Studies
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Study Purpose
This paper compared the effects of using a standard 18-gauge versus a 20-gauge needle in prostate biopsies on detection rates. Transrectal ultrasound-guided prostate biopsy (TRUSPB) was performed on 122 suspected prostate cancer cases with either an 18-gauge (62 cases) or 20-gauge (60 cases) needle with no significant difference in patient age, PSA level, prostate volume, or digital rectal examination (DRE) positive rates between the two groups. Cores were collected at the apex, middle, and base of the prostate on four vertical planes (right lateral, right medial, left medial, and left lateral) for a total of 12 biopsies from each patient. Gleason scores were determined by histological analysis by a single pathologist.
Summary of Findings:
Detection rates for prostate cancer were comparable between specimens obtained using a standard 18-gauge needle and a 20-gauge biopsy needle (40.3% and 35.0%, respectively; P > .05). Patients biopsied with a 20-gauge needle experienced fewer complications including pain, infection, hematuria, hematochezia, and dysuria than those biopsied with 18-gauge needles.
Biospecimens
Preservative Types
- Formalin
Diagnoses:
- Neoplastic - Carcinoma
Platform:
Analyte Technology Platform Cell count/volume H-and-E microscopy Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Biospecimen Acquisition Needle gauge 18G needle
20G needle