The impact of pneumatic tube transport on whole blood coagulation and platelet function assays.
Author(s): Nissen PH, Wulff DE, Tørring N, Hvas AM
Publication: Platelets, 2018, Vol. , Page 1-4
PubMed ID: 29442531 PubMed Review Paper? No
Purpose of Paper
This paper compared rotational thromboelastometry (ROTEM) parameters in blood specimens transported by pneumatic tube system with those transported by bicycle.
Conclusion of Paper
No external thromboelastometry (EXTEM), fibrin thromboelastometry (FIBTEM), or platelet parameters were significantly affected by transport by pneumatic tube system rather than bicycle. However, intrinisic thromboelastometry (INTEM) found transport by pneumatic tube rather than bicycle resulted in shorter clotting time and decreased maximum clot firmness (MCF) and A10 (clot amplitude at 10 minutes). The authors state that because these results indicate both increased coagulation activity (faster clot time) and impaired coagulation strength (decreased MCF and A10), it can be concluded that there were no systemic effects on coagulation.
Studies
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Study Purpose
This study compared ROTEM parameters in blood specimens transported by pneumatic tube system with those transported by bicycle. Blood was collected through 21-gauge needles into 3.5 mL sodium citrate tubes from 21 healthy adults. Specimens were transported 600 m by bicycle or 855 m by pneumatic tube at 3.7 m/sec. Blood coagulation was determined using ROTEM. Significance was determined to be P<0.003.
Summary of Findings:
No EXTEM, FIBTEM, or platelet parameters were significantly affected by transport by pneumatic tube system rather than bicycle. However, INTEM found transport by pneumatic tube rather than bicycle resulted in shorter clotting time (191 s versus 178 s, P=0.002) and decreased MCF (60 mm versus 62 mm, P<0.0001) and A10 (54 mm versus 55 mm, P<0.0001). The authors state that because these results indicate both increased coagulation activity (faster clot time) and impaired coagulation strength (decreased MCF and A10), it can be concluded that there were no systemic effects on coagulation.
Biospecimens
Preservative Types
- None (Fresh)
Diagnoses:
- Normal
Platform:
Analyte Technology Platform Morphology Thromboelastography Pre-analytical Factors:
Classification Pre-analytical Factor Value(s) Storage Within hospital transportation method Pneumatic tube system
Bicycle