NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

A clinical evaluation of a blood conservation device in medical intensive care unit patients.

Author(s): Peruzzi WT, Parker MA, Lichtenthal PR, Cochran-Zull C, Toth B, Blake M

Publication: Crit Care Med, 1993, Vol. 21, Page 501-6

PubMed ID: 8472567 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of using a blood conservation device (Venous arterial blood Management Protection (VAMP) system) on hemoglobin concentrations in blood from intensive care unit (ICU) patients.

Conclusion of Paper

After patients spent 228 hours in the ICU, specimens drawn with a VAMP system in place had significantly higher levels of hemoglobin than those drawn with no blood conservation device in the arterial catheter tubing system.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of using a VAMP system on hemoglobin concentrations in blood from ICU patients. Blood was sampled every 12 h during the patients' stay in the ICU.

    Summary of Findings:

    While both specimens collected with a VAMP system in place and those without showed decreases in hemoglobin concentrations over the length of the patients' stays in the ICU, after 228 hours, specimens drawn with a VAMP system in place had significantly higher levels of hemoglobin than those drawn with no blood conservation device in the arterial catheter tubing system. Prior to 228 hours, the differences in hemoglobin levels were not significant. Univariate linear regression analysis revealed that the volume of discarded blood, as well as other factors, was significantly associated with the decrease in hemoglobin concentration in specimens drawn as the duration of patient stays in the ICU increased. Use of the VAMP system significantly decreased the volume of discarded blood (p<0.0001).

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Protein Hematology/ auto analyzer
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Biospecimen Acquisition Time of biospecimen collection 0-250 h
    Biospecimen Acquisition Method of fluid acquisition Arterial catheter
    Blood-conserving sampling line

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