Evaluation of an improved blood-conserving POCT sampling system.

Author(s): Weiss M, Dullenkopf A, Moehrlen U

Publication: Clin Biochem, 2004, Vol. 37, Page 977-84

PubMed ID: 15498525 PubMed Review Paper? No

Purpose of Paper

Conclusion of Paper

Studies

1. Study Purpose

   The purpose of this study was to compare measurement of clinical chemistry and hematological analytes in blood collected directly into modified iSTAT sampling cartridges and collected in a syringe and transferred to an iSTAT cartridge. Hematocrit, sodium, potassium, calcium, glucose, bicarbonate, base excess, pH, hemoglobin, oxygen saturation, and partial pressure carbon dioxide and oxygen were measured using the iSTAT CG8+ cartridge on one of two similar iSTAT devices.

   Summary of Findings:

   There were no clinically relevant effects of sampling method on the measurement of any analytes, but potassium levels were elevated to a level which was statistically but not clinically significant when analyzed. However, this was only true for one of the two similar iSTAT machines tested.

   Biospecimens

   • Bodily Fluid - Blood

   Preservative Types

   • None (Fresh)

   Diagnoses:

   • Not specified

   Platform:

   Analyte	Technology Platform
   Carbohydrate	Clinical chemistry/auto analyzer
   Electrolyte/Metal	Clinical chemistry/auto analyzer
   Gas	Clinical chemistry/auto analyzer
   Cell count/volume	Hematology/ auto analyzer
   Small molecule	Clinical chemistry/auto analyzer

   Pre-analytical Factors:

   Classification	Pre-analytical Factor	Value(s)
   Biospecimen Acquisition	Method of fluid acquisition	Syringe draw Blood-conserving sampling line

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