NIH, National Cancer Institute, Division of Cancer Treatment and Diagnosis (DCTD) NIH - National Institutes of Health National Cancer Institute DCTD - Division of Cancer Treatment and Diagnosis

Stability of blood gases in ice and at room temperature.

Author(s): Liss HP, Payne CP Jr

Publication: Chest, 1993, Vol. 103, Page 1120-2

PubMed ID: 8131450 PubMed Review Paper? No

Purpose of Paper

The purpose of this paper was to determine the effects of storage on arterial blood gas and pH.

Conclusion of Paper

After only 15 minutes of storage, partial pressure oxygen (PO2) increased while partial pressure carbon dioxide (PCO2) and pH were significantly decreased. Changes in pO2, pCO2 and pH were not significantly different between specimens stored at room temperature and those stored on ice for up to 30 minutes. The authors conclude that for blood gas determinations, specimens can be stored at room temperature if analysis will be done within 30 minutes.

Studies

  1. Study Purpose

    The purpose of this study was to determine the effects of storage on arterial blood gas and pH.

    Summary of Findings:

    Changes in PO2, partial PCO2 and pH were not significantly different between specimens stored at room temperature and those stored on ice for up to 30 minutes. At both storage temperatures, PO2 increased after 15 minutes (p<0.001), and a further increase was found after 30 minutes (p<0.001). Whether stored on ice or at room temperature, PCO2 decreased after 15 minutes of storage (p=0.002-0.006). With storage at room temperature or on ice, pH decreased after 15 minutes (p=0.007-0.011) but a further decrease after 30 minutes was only significant in specimens stored at room temperature (p=0.003). The authors conclude that for blood gas determinations, specimens can be stored at room temperature if analysis will be done within 30 minutes.

    Biospecimens
    Preservative Types
    • None (Fresh)
    Diagnoses:
    • Not specified
    Platform:
    AnalyteTechnology Platform
    Gas Clinical chemistry/auto analyzer
    Small molecule pH
    Pre-analytical Factors:
    ClassificationPre-analytical FactorValue(s)
    Storage Storage temperature On ice
    Room temperature
    Storage Storage duration 0 min
    15 min
    30 min

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